Polyethylene Oxide MW 8,000,000 (PEO 8M, CAS 25322-68-3) is linear ultra-high molecular weight water-soluble polyether polymer suitable for veterinary pharmaceutical applications. When processed into veterinary solid preparations, PEO forms hydrated gel barrier after contacting body fluid. It effectively slows down the diffusion of active ingredients and achieves stable long-term drug release. The material features excellent binding performance and can enhance the hardness of veterinary tablets.

Product Detail

Product Overview

Polyethylene Oxide MW 8,000,000 (CAS 25322-68-3) is ultra-high molecular weight PEO specially developed for veterinary sustained-release formulations. Medium molecular weight PEO cannot maintain long-term controlled release effect; excessively high molecular weight grades lead to poor flowability and difficult tableting. This 8M grade balances sustained release performance, binding capacity and production processability.

After oral administration, the polymer gradually hydrates to build a gel layer on the tablet surface, restricting drug dissolution and extending action time inside animal digestive tract.

Key Features

Molecular Weight: 8,000,000, CAS 25322-68-3, white free-flowing fine powder
Form continuous hydrated gel to achieve stable controlled drug release
Prolong therapeutic effect and reduce frequent administration for livestock and poultry
Powerful binding property, improve tablet hardness and reduce tablet breakage
Low irritation to animal gastrointestinal tract, good biocompatibility
Excellent compatibility with various veterinary active pharmaceutical ingredients
Release rate adjustable by formulation and processing parameters

Main Applications

Sustained-release matrix for veterinary oral slow-release tablets and boluses
Water-soluble binder for livestock and poultry solid veterinary preparations
Film-forming slow-release excipient for animal deworming medicines
Functional additive for long-acting veterinary oral pharmaceutical formulations

Usage Guidance

Uniformly blend PEO powder with veterinary active components and other excipients. Employ direct compression or wet granulation process for tablet manufacturing. Adjust dosage according to target drug release curve. Complete dissolution test, hardness test and stability evaluation before mass production. Avoid overheating during processing to prevent molecular degradation.

Storage & Package

Hermetically sealed packaging. Store in cool, dry warehouse away from high temperature and direct sunlight. Standard package: 25kg moisture-proof kraft bag with inner PE liner. Shelf life: 12 months under proper sealed storage.

Service Support

Test samples available for veterinary medicine formula research. Stable bulk supply. We can supply COA, TDS and relevant technical guidance. Welcome to inquire factory quotation.

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Jishengya Technology

Shenzhen Jishengya Technology Co., Ltd. is located in Shenzhen, a special economic zone, and is a comprehensive technology enterprise integrating independent R&D, production and sales.